Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28750406 | 0.98 | NAPRT (0.47) | NAPRTALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL11146201 | 0.93 | NAPRT (0.48) | NAPRTALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL12567839 | 0.81 | PIK3CD (0.45) | CYP2C9NAMPTPRKCZMELKATM | |
| SCHEMBL5217117 | 0.81 | PRKCZ (0.43) | ALDH1A1HSD17B10NAMPTPRKCZMELK | |
| SCHEMBL8550093 | 0.81 | LMNA (0.58) | PRKCZLMNA | |
| SCHEMBL29574227 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL822307 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL29381755 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL14509008 | 0.79 | ALDH1A1 (0.50) | NAPRTALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL3822707 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117907492-B | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117907492-A | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117907492-B | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117907492-A | High performance liquid chromatography method for simultaneously qualitatively and quantitatively detecting 5-isoquinoline sulfonic acid and six impurities thereof | 山东新华制药股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-7375227-B2 | Quinoline derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-05-20 | — | — | US | disclosed |
| US-20050043535-A1 | 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043535-A1 | 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists | UTS2R, NTSR2, PLAUR | NAPRT 487/4885ALDH1A1 2993/4885HSD17B10 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.