SCHEMBL4856624

SCHEMBL4856624

c1ccc2c(c1)ccc1cc3c(ccc4cc5c(ccc6ccccc65)cc43)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
HSD17B10 Q99714 4/20 1.00
CYP1B1 Q16678 2/20 1.00
HIF1A Q16665 2/20 1.00
TSHR P16473 2/20 0.75
CYP2A6 P11509 1/20 0.75
TDP1 Q9NUW8 1/20 0.75
HPRT1 P00492 3/20 0.67
CYP1A2 P05177 3/20 0.60
HPGD P15428 3/20 0.60
PAX8 Q06710 1/20 0.52
TRPM4 Q8TD43 1/20 0.52
ERBB2 P04626 1/20 0.52
FYN P06241 1/20 0.52
MAOA P21397 1/20 0.52
ACHE P22303 1/20 0.52
AHR P35869 1/20 0.52
CYP1A1 P04798 1/20 0.50
MAPT P10636 1/20 0.50
CASP3 P42574 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenz[A,H]Anthracene SCHEMBL29392838 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
Dibenz[A,H]Anthracene SCHEMBL29777008 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
Dibenz[A,H]Anthracene SCHEMBL156100 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4852029 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4847673 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4845522 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL55324 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4852455 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4853205 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR
SCHEMBL4854152 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319266-B2 Syntheses, characterizations, and applications of heli-acenes University of Wyoming-Office of Research & Economic Development (US) 2022-05-03 US disclosed
US-20200354294-A1 SYNTHESES, CHARACTERIZATIONS, AND APPLICATIONS OF HELI-ACENES UNIVERSITY OF WYOMING (US) 2020-11-12 US disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-3965049-A One-step synthesis of aromatic organic diselenides XEROX CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319266-B2 Syntheses, characterizations, and applications of heli-acenes HRH1, EHD1, CRY1 ALDH1A1 1022/4885HSD17B10 335/4885CYP1B1 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.