Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | KAT7 | O95251 | 6/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.47 |
| ▸ | KAT6B | Q8WYB5 | 4/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008820 | 0.84 | KDM4E (0.52) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL554165 | 0.81 | MEN1 (0.49) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL27956815 | 0.80 | CYP3A4 (0.54) | PDE4BKMT2AGAAHTTMAPT | |
| SCHEMBL28853149 | 0.80 | ADRB2 (0.54) | PDE4BKAT7KAT6AKAT6BMEN1 | |
| SCHEMBL31172599 | 0.79 | MAPT (0.50) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL31172671 | 0.79 | HTT (0.56) | KAT7KAT6AKAT6BMEN1KMT2A | |
| SCHEMBL31172762 | 0.79 | HTT (0.56) | KAT7KAT6AKAT6BMEN1KMT2A | |
| SCHEMBL14610740 | 0.78 | GAA (0.44) | PDE4BGAAHTTTDP1MAPT | |
| SCHEMBL3809851 | 0.78 | TP53 (0.45) | PDE4BGAAHTTMAPTBRD4 | |
| SCHEMBL31172710 | 0.78 | MAPK1 (0.49) | KAT7KAT6AKAT6BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456169-B2 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | ABBVIE INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | MAP3K20, MAP3K19, MAP4K2 | PDE4B 890/4885KAT7 637/4885KAT6A 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.