Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29782851 | 0.86 | CD74 (0.50) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL20897187 | 0.85 | THRB (0.61) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10053919 | 0.81 | MEN1 (0.50) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL29008820 | 0.81 | KDM4E (0.52) | MAPTALDH1A1LMNATSHRHTT | |
| SCHEMBL10066968 | 0.80 | KMT2A (0.56) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL4857301 | 0.80 | PDE4B (0.55) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL27407526 | 0.79 | BRD4 (0.46) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10022368 | 0.78 | L3MBTL1 (0.49) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL554165 | 0.78 | MEN1 (0.49) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL4345848 | 0.78 | KMT2A (0.54) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-B | Thienopyrimidine derivative, its preparation method and the Pharmaceutical composition containing them | 法国施维雅药厂 | 2017-11-28 | — | — | CN | disclosed |