Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956815 | 0.84 | CYP3A4 (0.54) | GAAMAPTBRD4PDE4BCYP3A4 | |
| SCHEMBL3809851 | 0.81 | TP53 (0.45) | GAAMAPTBRD4F2F10 | |
| SCHEMBL5299707 | 0.81 | BRD4 (0.43) | GAAMAPTBRD4HDAC1HDAC6 | |
| SCHEMBL28851379 | 0.81 | GAA (0.46) | GAAMAPTBRD4F2F10 | |
| SCHEMBL16403546 | 0.79 | CA12 (0.51) | GAAMAPTBRD4F2F10 | |
| SCHEMBL5301838 | 0.78 | CCR1 (0.54) | F2F10CYP3A4CYP2C9 | |
| SCHEMBL4857301 | 0.78 | PDE4B (0.55) | GAAMAPTBRD4PDE4BTDP1 | |
| SCHEMBL16403337 | 0.77 | GAA (0.49) | GAAMAPTBRD4F2F10 | |
| SCHEMBL16410194 | 0.76 | GAA (0.48) | GAAMAPTBRD4F2F10 | |
| SCHEMBL7445529 | 0.75 | CCR1 (0.50) | BRD4F2F10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159805-A1 | Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159805-A1 | Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159805-A1 | Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | US | disclosed |
| EP-3021673-A1 | HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES | Bayer CropScience Aktiengesellschaft (DE) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015007668-A1 | HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015007668-A1 | HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2015-01-22 | — | — | WO | disclosed |
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159805-A1 | Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties | TST, TUBB, TUBA3C | GAA 2256/4885MAPT 4347/4885BRD4 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.