Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748425 | 0.79 | KDM4E (0.40) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL1188 | 0.79 | — | — | |
| SCHEMBL9739814 | 0.76 | FGFR1 (0.50) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9740964 | 0.73 | NPC1 (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5441549 | 0.72 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL18315984 | 0.71 | GPR84 (0.50) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| Anthracene SCHEMBL29352043 | 0.71 | CYP2A6 (0.64) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| Anthracene SCHEMBL7703 | 0.71 | CYP2A6 (0.64) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| Anthracene SCHEMBL2833889 | 0.71 | CYP2A6 (0.64) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| Anthracene SCHEMBL5713429 | 0.71 | CYP2A6 (0.64) | MAPTKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-07 | — | — | US | claimed |
| US-20210371367-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-02 | — | — | US | claimed |
| CN-111712481-A | Triarylmethane compounds | 三菱瓦斯化学株式会社 | 2020-09-25 | — | — | CN | claimed |
| EP-4365176-A1 | KRAS G12D INHIBITOR AND USE THEREOF | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2024-05-08 | — | — | EP | disclosed |
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-07 | — | — | US | disclosed |
| US-11760712-B2 | Triarylmethane compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| WO-2023274383-A1 | KRAS G12D INHIBITOR AND USE THEREOF | 上海迪诺医药科技有限公司 | 2023-01-05 | — | — | WO | disclosed |
| US-20210371367-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | disclosed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | disclosed |
| CN-111712481-A | Triarylmethane compounds | 三菱瓦斯化学株式会社 | 2020-09-25 | — | — | CN | disclosed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | disclosed |
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | NISHIO TETSUYA | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | MAPT 4484/4885KDM4E 1132/4885MEN1 3144/4885 |
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | CBR3, HAX1, HRH3 | MAPT 4486/4885KDM4E 1561/4885MEN1 3609/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | MAPT 4486/4885KDM4E 965/4885MEN1 3753/4885 |
| US-11760712-B2 | Triarylmethane compounds | CBR3, HAX1, HRH3 | MAPT 4486/4885KDM4E 1561/4885MEN1 3609/4885 |
| US-20210371367-A1 | TRIARYLMETHANE COMPOUNDS | CBR3, HAX1, HRH3 | MAPT 4486/4885KDM4E 1561/4885MEN1 3609/4885 |
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | PIEZO1, YES1, SAT1 | MAPT 1211/4885KDM4E 710/4885MEN1 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.