SCHEMBL4955690

SCHEMBL4955690

CCCCCCC=C[Si](C)(C)O[Si](C)(C)C=CCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.45
TRPV1 Q8NER1 1/20 0.45
TERT O14746 3/20 0.39
PTPN1 P18031 3/20 0.39
CYP1A2 P05177 2/20 0.39
MAPT P10636 2/20 0.39
CYP2C19 P33261 2/20 0.39
BLM P54132 2/20 0.39
HSD17B10 Q99714 2/20 0.39
FABP4 P15090 2/20 0.39
PPARG P37231 2/20 0.39
KMT2A Q03164 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18380870 0.92 FAAH (0.42) FAAHTRPV1TERTPTPN1CYP1A2
SCHEMBL2574424 0.91 TSHR (0.35) FAAHTRPV1MAPTKMT2AF7
SCHEMBL2574423 0.91 TSHR (0.35) FAAHTRPV1MAPTKMT2AF7
SCHEMBL9929506 0.85 FAAH (0.43) FAAHTRPV1TERTPTPN1CYP1A2
SCHEMBL30422740 0.85 FAAH (0.43) FAAHTRPV1TERTPTPN1CYP1A2
SCHEMBL29911010 0.83 FAAH (0.42) FAAHTRPV1TERTPTPN1CYP1A2
SCHEMBL4858752 0.83 TSHR (0.32) FAAHTRPV1F7F3
SCHEMBL4858746 0.83 TSHR (0.32) FAAHTRPV1F7F3
SCHEMBL27620279 0.83 TSHR (0.32) FAAHTRPV1F7F3
Water SCHEMBL27620281 0.81 TSHR (0.31) FAAHTRPV1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7322927-B2 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2008-01-29 US disclosed
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses BIOSITE INCORPORATED 2006-10-12 US disclosed
US-7083984-B2 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2006-08-01 US disclosed
US-6964844-B1 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2005-11-15 US disclosed
US-20020061602-A1 Hybrid phthalocyanine derivatives and their uses GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-05-23 US disclosed
EP-0670041-B1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INC (US) 2002-01-30 EP disclosed
US-6251687-B1 PARTICLE CONTAINING ENERGY DONOR AND ENERGY ACCEPTOR BIOSITE DIAGNOSTICS, INC. 2001-06-26 US disclosed
EP-0820489-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INC. (US) 1998-01-28 EP disclosed
EP-0670041-A4 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS. BIOSITE DIAGNOSTICS INC (US) 1997-11-05 EP disclosed
WO-1996029367-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INCORPORATED (US) 1996-09-26 WO disclosed
EP-0670041-A1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INC. (US) 1995-09-06 EP disclosed
WO-1995008772-A1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INCORPORATED (US) 1995-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses UACA, PHAX, PTBP1 FAAH 4871/4885TRPV1 2238/4885TERT 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.