SCHEMBL4858880

SCHEMBL4858880

Nc1ccccc1Oc1ccc(C(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
RCE1 Q9Y256 1/20 0.45
IKBKB O14920 4/20 0.43
BRAF P15056 1/20 0.43
LTA4H P09960 1/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
ALDH1A1 P00352 3/20 0.40
TLR4 O00206 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
RAB9A P51151 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2C19 P33261 3/20 0.35
CYP3A4 P08684 2/20 0.35
ADRA2B P18089 1/20 0.34
PTGS1 P23219 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2C9 P11712 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8825487 0.86 L3MBTL1 (0.33) GAARCE1IKBKBBRAFLTA4H
SCHEMBL27940216 0.82 L3MBTL1 (0.43) GAARCE1MAPTKDM4EALDH1A1
SCHEMBL28956106 0.81 NCOA1 (0.38) GAALTA4HMAPTALDH1A1RAB9A
SCHEMBL3146062 0.79 ALDH1A1 (0.50) GAALTA4HMAPTALDH1A1RAB9A
SCHEMBL16738115 0.78 KDM4E (0.43) GAARCE1IKBKBBRAFMAPT
SCHEMBL8502827 0.77 KDM4E (0.44) GAARCE1MAPTKDM4ECRHBP
SCHEMBL8541421 0.77 NR4A1 (0.53) GAAMAPTALDH1A1L3MBTL1RAB9A
SCHEMBL9449292 0.76 KMT2A (0.40) GAAMAPTKDM4ECRHBPCRHR2
SCHEMBL2285909 0.76 GAA (0.69) GAARCE1IKBKBBRAFLTA4H
SCHEMBL297848 0.76 GAA (0.45) GAARCE1IKBKBBRAFLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891570-A Polyamic acid, polyimide, metal-clad laminate, and circuit board 日铁化学材料株式会社 2023-10-17 CN disclosed
CN-113874420-B Resin film and metal-clad laminate 日铁化学材料株式会社 2023-09-26 CN disclosed
CN-116353168-A Resin laminate, circuit board, electronic component, and electronic device 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-116367413-A Metal-clad laminate and circuit board 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-113874420-A Resin film, metal-clad laminate, and method for producing same 日铁化学材料株式会社 2021-12-31 CN disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-5856065-A BLEND CONTAINING PHOTOINITIATOR AND ORGANOSILICON COMPOUND OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-01-05 US disclosed