Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547639 | 0.91 | ESR1 (0.50) | ESR1ESR2EPHX1OPRD1 | |
| SCHEMBL19272442 | 0.85 | ESR1 (0.45) | ESR1ESR2TSHRTP53PDE4A | |
| SCHEMBL764935 | 0.82 | PTGS1 (0.46) | ESR1TSHRTP53PDE4APTGS1 | |
| SCHEMBL7806637 | 0.80 | ESR1 (0.76) | ESR1ESR2CYP2C9 | |
| SCHEMBL10456186 | 0.80 | ESR1 (0.76) | ESR1ESR2TSHRCYP2C9SLC6A4 | |
| SCHEMBL572776 | 0.80 | ESR1 (0.76) | ESR1ESR2CYP2C9 | |
| SCHEMBL12040182 | 0.80 | RORC (0.46) | TSHRCYP2C9GRIA4OPRD1 | |
| SCHEMBL24533708 | 0.78 | GRIA4 (0.38) | ESR1ESR2PDE4ALMNACYP2C9 | |
| SCHEMBL23854927 | 0.77 | ESR1 (0.50) | ESR1ESR2TSHRTP53SLC6A4 | |
| SCHEMBL10600155 | 0.77 | ESR1 (0.55) | ESR1ESR2PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323284-B2 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20030022095-A1 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2003-01-30 | — | — | US | disclosed |