Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 7/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184308 | 0.82 | ALDH1A1 (0.51) | LMNACYP2C9 | |
| SCHEMBL2557310 | 0.80 | ESR1 (0.71) | ESR1ESR2CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL4859307 | 0.77 | ESR1 (0.60) | ESR1ESR2SLC6A4PTGS2LMNA | |
| SCHEMBL10338355 | 0.76 | CYP1A2 (0.63) | ESR1ESR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9845872 | 0.75 | ESR1 (0.58) | ESR1ESR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL24233182 | 0.73 | ALDH1A1 (0.48) | ESR1ESR2CNR1ACACBSLC6A4 | |
| SCHEMBL10596460 | 0.73 | CYP17A1 (0.44) | ESR1CYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL19968620 | 0.72 | ESR1 (0.55) | ESR1ESR2PTGS2LMNAALB | |
| SCHEMBL5500322 | 0.72 | ESR1 (0.55) | ESR1ESR2PPARGPPARAPTGS2 | |
| SCHEMBL10493597 | 0.72 | LMNA (0.55) | ESR1ESR2CNR1ACACBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197806-B1 | ADHESIVE LAYER BASED ON POLYURETHANE, AND ITS USE IN LAMINATED GLASS | SAINT GOBAIN VITRAGE INTERNATIONAL (FR) | 1989-04-19 | — | — | EP | disclosed |