Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918492 | 0.85 | RIPK1 (0.46) | GRIA4RIPK1ESR1ESR2 | |
| SCHEMBL12040182 | 0.82 | RORC (0.46) | GRIA4OPRD1CYP2C9RORC | |
| SCHEMBL15854207 | 0.79 | ESR1 (0.55) | RIPK1CYP2D6CYP2C9HIF1AESR1 | |
| SCHEMBL8373596 | 0.79 | ESR1 (0.55) | RIPK1CYP2D6CYP2C9HIF1AESR1 | |
| SCHEMBL4859307 | 0.78 | ESR1 (0.60) | GRIA4OPRD1CYP2C9ESR1ESR2 | |
| SCHEMBL19173395 | 0.78 | OPRD1 (0.36) | OPRD1CYP2D6CYP2C9HIF1AKCNH2 | |
| SCHEMBL19221989 | 0.77 | HDAC8 (0.40) | GRIA4OPRD1CYP2D6CYP2C9HIF1A | |
| SCHEMBL565578 | 0.76 | CYP2C9 (0.57) | OPRD1CYP2D6CYP2C9HIF1APDE2A | |
| SCHEMBL21934758 | 0.76 | OPRD1 (0.35) | OPRD1CYP2D6CYP2C9HIF1AKCNH2 | |
| SCHEMBL10831182 | 0.76 | GRIA4 (0.38) | GRIA4OPRD1CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220197140-A1 | ALCOHOL COMPOUND, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-06-23 | — | — | US | disclosed |