Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107873 | 0.89 | HDAC3 (0.65) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL1039187 | 0.83 | NR1H2 (0.59) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL11994463 | 0.81 | HDAC3 (0.53) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL1040640 | 0.80 | HDAC3 (0.56) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL15299350 | 0.80 | HDAC3 (0.60) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL5374900 | 0.80 | MAP2K4 (0.47) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL13545717 | 0.79 | NOTUM (0.52) | HDAC3HDAC6NCOR2RAB9AIKBKB | |
| SCHEMBL1436121 | 0.79 | NR1H2 (0.61) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL9465116 | 0.78 | NR1H2 (0.50) | NR1H2NR1H3HDAC3HDAC6NCOR2 | |
| SCHEMBL16661177 | 0.78 | HDAC3 (0.46) | NR1H2NR1H3HDAC3HDAC6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169148-A | Method of treating inflammatory and psychotic conditions with 1,2,4 triazole derivatives and compositions containing same | E. R. SQUIBB & SONS, INC. (US) | 1979-09-25 | — | — | US | claimed |
| US-7423036-B2 | Long-acting betamimetics for the treatment of respiratory complaints | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-09 | — | — | US | disclosed |
| CN-1307282-C | High molicular luminescent material of enery transfusion type poly(p-phenylene ethylene) like and it preparation process | CHANGCHUN APPLIED CHEMISTRY (CN) | 2007-03-28 | — | — | CN | disclosed |
| CN-1300195-C | Energy-transfer poly(p-phenylene vinylene) polymer light-emitting materials and process for preparing same | CHANGCHUN APPLIED CHEMISTRY (CN) | 2007-02-14 | — | — | CN | disclosed |
| US-20060189607-A1 | Long-acting betamimetics for the treatment of respiratory complaints | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-24 | — | — | US | disclosed |
| CN-1693415-A | High molicular luminescent material of enery transfusion type poly(p-phenylene ethylene) like and it preparation process | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-11-09 | — | — | CN | disclosed |
| CN-1690095-A | Energy-transfer poly(p-phenylene vinylene) polymer light-emitting materials and process for preparing same | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-11-02 | — | — | CN | disclosed |
| CN-1221580-C | Energy transfer type poly (p-phenylene ethylene) high molecular luminescent material and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-10-05 | — | — | CN | disclosed |
| CN-1454962-A | Energy transfer type poly (p-phenylene ethylene) high molecular luminescent material and preparation method thereof | CHANG CHUN APPLIED CHEMISTRY I (CN) | 2003-11-12 | — | — | CN | disclosed |
| US-4332812-A | ANTIARTHRITIC | E. R. SQUIBB & SONS, INC. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4169148-A | Method of treating inflammatory and psychotic conditions with 1,2,4 triazole derivatives and compositions containing same | E. R. SQUIBB & SONS, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4127587-A | ANTIINFLAMMATORY, ANTHELMINTIC | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4093728-A | ANTIINFLAMMATORY AGENTS, ANTHELMINTICS | E. R. SQUIBB & SONS, INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4076823-A | ANTIINFLAMMATORY, MUSCLE RELAXANT, ANXIOLYTIC, SEDATIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189607-A1 | Long-acting betamimetics for the treatment of respiratory complaints | ADRA1A, ADRA1D, ADRA2A | NR1H2 783/4885NR1H3 1068/4885HDAC3 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.