SCHEMBL4859534

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4856652	0.82	CYP11B2 (0.40)	KDM4EL3MBTL1MAPTMCHR1ACHE
	SCHEMBL4858109	0.81	ACHE (0.38)	KDM4EL3MBTL1MAPTHPGDHTR1A
	SCHEMBL6034199	0.78	THRA (0.46)	L3MBTL1MAPTACHEALDH1A1SMN1; SMN2
	SCHEMBL4889684	0.78	MCHR1 (0.39)	KDM4EL3MBTL1MCHR1ACHETSHR
	SCHEMBL4889668	0.78	MCHR1 (0.36)	KDM4EL3MBTL1MAPTHPGDHTR1A
	Hydrochloric Acid SCHEMBL4853622	0.78	THRA (0.45)	L3MBTL1MAPTACHEALDH1A1SMN1; SMN2
	SCHEMBL6035073	0.78	MCHR1 (0.38)	BRD4BRD2BRD3KDM4EL3MBTL1
	Hydrochloric Acid SCHEMBL4857673	0.77	MCHR1 (0.38)	BRD4BRD2BRD3KDM4EL3MBTL1
	SCHEMBL27611240	0.77	TSHR (0.35)	BRD4BRD2BRD3KDM4EL3MBTL1
	SCHEMBL13988069	0.76	KMT2A (0.38)	BRD4BRD2BRD3KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.