Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HRH2 | P25021 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852957 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9ANOD2LMNA | |
| SCHEMBL773204 | 0.59 | NR4A3 (0.78) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL5206324 | 0.57 | SLC2A1 (0.50) | ALDH1A1LMNAHTTNPSR1POLB | |
| SCHEMBL16615597 | 0.57 | ALDH1A1 (0.74) | ALDH1A1LMNANPSR1MAPTMAPK1 | |
| SCHEMBL13593554 | 0.56 | ALDH1A1 (0.63) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL4851314 | 0.56 | HTR6 (0.45) | ALDH1A1NPC1RAB9ANOD2LMNA | |
| SCHEMBL27808 | 0.56 | NR4A3 (0.61) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL14927230 | 0.56 | RAB9A (0.78) | ALDH1A1NPC1RAB9ANOD2LMNA | |
| SCHEMBL1549166 | 0.56 | MAPT (0.76) | ALDH1A1NPC1RAB9ANOD2LMNA | |
| SCHEMBL2857718 | 0.56 | ALDH1A1 (0.69) | ALDH1A1LMNAPOLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368470-B2 | Substituted 3-pyrrolidine-indole derivatives | GRUENENTHAL GMBH (DE) | 2008-05-06 | — | — | US | disclosed |