Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375006 | 0.69 | TDO2 (0.45) | CCNT1PIM1CDK9HASPIN | |
| SCHEMBL6466793 | 0.62 | ATM (0.34) | HTR6GSK3B | |
| SCHEMBL31530815 | 0.61 | MAPT (0.48) | HTR6 | |
| SCHEMBL2001443 | 0.60 | CDK2 (0.40) | HTR6PIM1HASPINNFATC1GSK3B | |
| SCHEMBL21819208 | 0.60 | PIK3CB (0.32) | — | |
| SCHEMBL9377656 | 0.59 | HTR6 (0.39) | HTR6PIM1HASPINNFATC1GSK3B | |
| SCHEMBL10587 | 0.59 | PIM1 (0.59) | HTR6CCNT1PIM1CDK9HASPIN | |
| SCHEMBL16168495 | 0.59 | HTR6 (0.56) | HTR6CCNT1PIM1CDK9HASPIN | |
| SCHEMBL3224448 | 0.59 | ATM (0.52) | HTR6CCNT1PIM1CDK9HASPIN | |
| SCHEMBL2050489 | 0.59 | HASPIN (0.59) | HTR6CCNT1PIM1CDK9HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157740-A2 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |