Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11914057 | 0.75 | L3MBTL1 (0.40) | L3MBTL1BTKCTSDBACE1BACE2 | |
| SCHEMBL15000459 | 0.70 | L3MBTL1 (0.39) | L3MBTL1 | |
| SCHEMBL15650950 | 0.70 | L3MBTL1 (0.44) | L3MBTL1BTKCTSDBACE1BACE2 | |
| SCHEMBL25123375 | 0.69 | KDR (0.39) | L3MBTL1 | |
| SCHEMBL15000464 | 0.69 | KDR (0.39) | L3MBTL1 | |
| SCHEMBL24611400 | 0.69 | KDR (0.39) | L3MBTL1 | |
| SCHEMBL674823 | 0.68 | L3MBTL1 (0.37) | L3MBTL1 | |
| SCHEMBL299543 | 0.68 | LMNA (0.43) | L3MBTL1CTSDBACE1BACE2 | |
| SCHEMBL299542 | 0.66 | L3MBTL1 (0.41) | L3MBTL1BTKCTSDBACE1BACE2 | |
| SCHEMBL11084604 | 0.66 | L3MBTL1 (0.44) | L3MBTL1CTSDBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411388-A2 | PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES | Elan Pharmaceuticals Inc. (US) | 2012-02-01 | — | — | EP | claimed |
| EP-2411388-A2 | PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES | Elan Pharmaceuticals Inc. (US) | 2012-02-01 | — | — | EP | disclosed |