Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22237505 | 0.80 | MGAT2 (0.31) | — | |
| SCHEMBL19159122 | 0.74 | LMNA (0.42) | L3MBTL1KDRSMPD1 | |
| SCHEMBL16131370 | 0.73 | — | — | |
| SCHEMBL1228571 | 0.73 | ALDH1A1 (0.41) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL6571556 | 0.73 | LMNA (0.41) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL9625648 | 0.73 | LMNA (0.41) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL2951930 | 0.73 | L3MBTL1 (0.40) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL6054614 | 0.73 | L3MBTL1 (0.40) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL294214 | 0.73 | LMNA (0.41) | L3MBTL1KDRSMPD1GBA1 | |
| SCHEMBL19608592 | 0.73 | LMNA (0.41) | L3MBTL1KDRSMPD1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213329-B | Preparation method of aryl pyrazole compound | 中国农业科学院兰州畜牧与兽药研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-114213329-A | Preparation method of arylpyrazole compound | 中国农业科学院兰州畜牧与兽药研究所 | 2022-03-22 | — | — | CN | disclosed |
| US-8084486-B2 | Substituted arylpyrazoles | PFIZER LIMITED (GB) | 2011-12-27 | — | — | US | disclosed |
| US-20110196011-A1 | SUBSTITUTED ARYLPYRAZOLES | PFIZER LIMITED (GB) | 2011-08-11 | — | — | US | disclosed |
| US-7968584-B2 | Substituted arylpyrazoles | PFIZER INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-7968584-B2 | Substituted arylpyrazoles | PFIZER INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-7960426-B2 | Substituted arylpyrazoles | PFIZER LIMITED (GB) | 2011-06-14 | — | — | US | disclosed |
| US-7902232-B2 | Substituted arylpyrazoles | PFIZER LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| US-7902232-B2 | Substituted arylpyrazoles | PFIZER LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| EP-1893581-B1 | SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES | PFIZER LTD (GB) | 2010-01-27 | — | — | EP | disclosed |
| US-20020173662-A1 | Parasiticidal pyrazoles | BANKS BERNARD JOSEPH (GB) | 2002-11-21 | — | — | US | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6090394-A | FOR HUMANS, ANIMALS | PFIZER INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-6077859-A | Pyrazoles | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |
| US-6019986-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0959071-A1 | 1-Aryl-4-cycloalk(en)ylpyrazoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0946515-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-10-06 | — | — | EP | disclosed |
| EP-0933363-A1 | Parasiticidal pyrazoles | Pfizer Limited (GB) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998024767-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196011-A1 | SUBSTITUTED ARYLPYRAZOLES | CYP4X1, EPX, CYP2C9 | L3MBTL1 1016/4885SPHK1 3914/4885KDR 3607/4885 |
| US-20020173662-A1 | Parasiticidal pyrazoles | HRH3, HRH2, HRH1 | L3MBTL1 953/4885SPHK1 3399/4885KDR 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.