Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802651 | 0.82 | TEAD1 (0.53) | CYP3A4MAPTMAPK1EPHX2DRD2 | |
| SCHEMBL3797549 | 0.74 | HRH2 (0.45) | ALDH1A1CCR5HRH3EPHX2 | |
| SCHEMBL3631495 | 0.71 | TEAD1 (0.52) | L3MBTL1EPHX2DRD2DRD4SLC6A5 | |
| SCHEMBL2804476 | 0.71 | TEAD1 (0.56) | CYP3A4MAPTMAPK1HRH3DRD2 | |
| SCHEMBL2808223 | 0.71 | BCHE (0.51) | MMP13HRH3EPHX2 | |
| SCHEMBL14216185 | 0.70 | ACHE (0.45) | MMP1MMP13HRH3DRD4 | |
| SCHEMBL2802531 | 0.69 | TEAD1 (0.54) | HRH3DRD2DRD4SLC6A5 | |
| SCHEMBL2802000 | 0.69 | TEAD1 (0.53) | KDM4EALDH1A1MCHR1EPHX2DRD2 | |
| SCHEMBL14476853 | 0.68 | TSHR (0.57) | PTPN1MAPTHRH3 | |
| SCHEMBL3629314 | 0.66 | TEAD1 (0.58) | MCHR1HRH3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140450-A1 | METHODS OF TREATMENT AND PREVENTION OF METABOLIC BONE DISEASES AND DISORDERS | THOMAS JEFFERSON UNIVERSITY (US) | 2008-11-20 | — | — | WO | disclosed |