SCHEMBL2804476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2802531	0.91	TEAD1 (0.54)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL2802000	0.90	TEAD1 (0.53)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL2802651	0.89	TEAD1 (0.53)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL3629314	0.89	TEAD1 (0.58)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL3631495	0.89	TEAD1 (0.52)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL14223080	0.87	ACHE (0.48)	TEAD1BCHEACHEBACE1DRD4
	SCHEMBL3797015	0.87	BCHE (0.54)	TEAD1BCHEACHEBACE1DRD4
	SCHEMBL4569598	0.82	TEAD1 (0.53)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL3457225	0.81	TEAD1 (0.61)	TEAD1BCHEACHEBACE1PHGDH
	SCHEMBL14223527	0.81	SLC6A3 (0.39)	TEAD1DRD4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.