Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | FOS | P01100 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160151 | 0.88 | MEN1 (0.54) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL3540132 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL7821958 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL7821956 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL4443606 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL490213 | 0.81 | THRB (0.50) | ALDH1A1BCHEMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30560128 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2AFOSJUN | |
| SCHEMBL4906426 | 0.81 | THRB (0.50) | ALDH1A1BCHEMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4879128 | 0.81 | THRB (0.50) | ALDH1A1BCHEMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5319436 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AFOSJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156654-A2 | CYTOSKELETON MODULATORS FOR TREATING METABOLIC DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-12-24 | — | — | WO | disclosed |