SCHEMBL490213

SCHEMBL490213

COc1ccc(C=C(C(=O)O)C(C)C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
AKR1C3 P42330 1/20 0.48
F3 P13726 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
NFKB1 P19838 2/20 0.46
TSHR P16473 1/20 0.46
APEX1 P27695 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CYP2A6 P11509 1/20 0.46
GSK3B P49841 2/20 0.45
BACE1 P56817 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4879128 1.00 THRB (0.50) THRBATMALDH1A1KDM4EMAPT
SCHEMBL4906426 1.00 THRB (0.50) THRBATMALDH1A1KDM4EMAPT
SCHEMBL8153615 0.87 CYP1A2 (0.52) THRBATMALDH1A1KDM4EMAPT
SCHEMBL16160027 0.86 ALDH1A1 (0.49) THRBATMALDH1A1KDM4EMAPT
SCHEMBL16266991 0.85 THRB (0.49) THRBATMALDH1A1KDM4EMAPT
SCHEMBL4896165 0.84 THRB (0.45) THRBATMALDH1A1KDM4EMAPT
SCHEMBL4896183 0.84 THRB (0.45) THRBATMALDH1A1KDM4EMAPT
SCHEMBL5085450 0.82 THRB (0.43) THRBATMALDH1A1KDM4EMAPT
SCHEMBL4861174 0.81 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTSMN1; SMN2CYP1A2
SCHEMBL4896172 0.81 LMNA (0.48) THRBATMALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10620481-B2 Optical alignment film composition, optical alignment film, optical laminate, and image display device FUJIFILM CORPORATION (JP) 2020-04-14 US claimed
EP-2662068-B1 OIL-IN-WATER EMULSION COMPOSITION KAO CORP (JP) 2017-07-05 EP claimed
EP-2913052-A1 Phototherapy compositions and methods OMJ Ireland Limited (PR) 2015-09-02 EP claimed
US-8772224-B2 Perfuming solution stabilized with respect to ultraviolet radiation LVMH RECHERCHE (FR) 2014-07-08 US claimed
US-20130045913-A1 PERFUMING SOLUTION STABILIZED WITH RESPECT TO ULTRAVIOLET RADIATION LVMH RECHERCHE (FR) 2013-02-21 US claimed
EP-1595936-B1 COMPOSITION FOR EXTERNAL USE VITAMIN C60 BIORES CORP (JP) 2011-10-19 EP claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008083974-A1 ACTIVE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO claimed
EP-0308543-B1 COMPOSITIONS FOR EXTERNAL APPLICATION Sansho Seiyaku Co., Ltd. (JP) 1993-09-22 EP claimed
WO-2026106274-A1 HAIR COSMETIC COMPOSITION HAVING EXCELLENT PHOTOPROTECTIVE EFFICACY 한국콜마주식회사 2026-05-21 WO disclosed
WO-2026105865-A1 STRATUM CORNEUM LAYER RETENTION IMPROVER, SHININESS INHIBITOR, AND SKIN EXTERNAL COMPOSITION CONTAINING SAME 日清オイリオグループ株式会社 2026-05-21 WO disclosed
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof MEDIHELPLINE CO., LTD (KR) 2026-05-05 US disclosed
US-12589062-B2 Powdery solid cosmetic preparation SHISEIDO COMPANY, LTD. (JP) 2026-03-31 US disclosed
US-6150425-A COMPRISING AN OUTER PHASE OIL AND OIL IN WATER EMULSION IN THE INNER PHASE WHICH CONTAINING WATER, AN OIL BASED INGREDIENT, A SURFACTANT AND AN AMPHIPHILIC SUBSTANCE; PREPARED BY A HIGH PRESSURE OR ULTRASONIC EMULSIFICATION SHISEIDO COMPANY, LTD. (JP) 2000-11-21 US disclosed
WO-2000057840-A2 DERMATOLOGICAL TOPICAL COMPOSITION PENTAPHARM AG (CH) 2000-10-05 WO disclosed
EP-1002515-A1 SKIN COMPOSITIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2000-05-24 EP disclosed
EP-0970741-A1 O/W/O TYPE MULTIPHASE EMULSION SHISEIDO COMPANY LIMITED (JP) 2000-01-12 EP disclosed
EP-0887070-A1 External composition for skin comprising sphingoglycolipid Kibun Food ChemiFA Co., Ltd. (JP) 1998-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589062-B2 Powdery solid cosmetic preparation TMEM63A, CUTA, VCL THRB 690/4885ATM 214/4885ALDH1A1 4594/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 THRB 1148/4885ATM 567/4885ALDH1A1 28/4885
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof CUTA, VEGFA, MMP8 THRB 1180/4885ATM 453/4885ALDH1A1 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.