SCHEMBL4861365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4859871	0.91	PKM (0.43)	PKMHTTPDE4DPDE4APDE4B
	SCHEMBL4862327	0.90	PKM (0.50)	PKMHTTPDE4DLPAR1PDE4A
	SCHEMBL4861490	0.89	PKM (0.41)	PKMTDP1ACHE
	SCHEMBL5313256	0.87	PKM (0.39)	PKMHTTPDE4DPDE4APDE4B
	SCHEMBL4855030	0.85	KMT2A (0.42)	HTTPDE4DLPAR1PDE4APDE4B
	SCHEMBL4851734	0.84	KMT2A (0.41)	HTTPDE4DLPAR1PDE4APDE4B
	SCHEMBL4859697	0.83	PKM (0.48)	PKMHTTALDH1A1TDP1ACHE
	SCHEMBL4862735	0.81	SMN1; SMN2 (0.46)	LMNAL3MBTL1ALDH1A1TDP1CA12
	SCHEMBL4851706	0.80	PKM (0.46)	PKMHTTKMT2AALDH1A1TDP1
	SCHEMBL5576909	0.79	PKM (0.43)	PKMHTTPDE4DPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.