SCHEMBL4859871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5313256	0.93	PKM (0.39)	PKMACHEPTGES2TDP1TSHR
	SCHEMBL4861490	0.92	PKM (0.41)	PKMACHETDP1P2RX4
	SCHEMBL4861365	0.91	PKM (0.46)	PKMACHETDP1KMT2AHTT
	SCHEMBL4859697	0.90	PKM (0.48)	PKMACHEPTGES2TDP1TSHR
	SCHEMBL5329226	0.88	ACHE (0.37)	PKMACHEPTGES2BCHEAOC3
	SCHEMBL4859853	0.87	NPSR1 (0.48)	PKMACHETDP1BCHEMEN1
	SCHEMBL4856412	0.85	ALDH1A1 (0.40)	ACHEBCHEMEN1KMT2ASMN1; SMN2
	SCHEMBL4855046	0.85	CTNNB1 (0.39)	ACHEPTGES2TDP1BCHESMN1; SMN2
	SCHEMBL4860745	0.84	ALDH1A1 (0.39)	ACHEBCHEMEN1KMT2ASMN1; SMN2
	SCHEMBL5576909	0.84	PKM (0.43)	PKMACHETDP1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.