SCHEMBL4861482

SCHEMBL4861482

COP1(=O)Oc2ccccc2-c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
CYP2C19 P33261 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30802135 1.00 KDM4E (0.31) KDM4EMAP2K7GMNNALDH1A1LMNA
SCHEMBL18516976 0.86
SCHEMBL20834234 0.83
SCHEMBL13278322 0.82 HSP90AA1 (0.31) HSP90AA1
SCHEMBL28788036 0.81
SCHEMBL17223250 0.81 ALDH1A1 (0.31) KDM4EALDH1A1MAPT
SCHEMBL16470148 0.81 HSP90AA1 (0.30) HSP90AA1
SCHEMBL16470217 0.81 ALDH1A1 (0.31) ALDH1A1HSP90AA1
SCHEMBL16469669 0.81 HSP90AA1 (0.30) HSP90AA1
SCHEMBL31212350 0.79 RECQL (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738774-B2 Flame retardant for epoxy resin containing phosphonate and phosphinate functionality ICL-IP AMERICA INC. (US) 2017-08-22 US disclosed
US-9738774-B2 Flame retardant for epoxy resin containing phosphonate and phosphinate functionality ICL-IP AMERICA INC. (US) 2017-08-22 US disclosed
US-20160244596-A1 FLAME RETARDANT FOR EPOXY RESIN CONTAINING PHOSPHONATE AND PHOSPHINATE FUNCTIONALITY ICL-IP AMERICA INC. 2016-08-25 US disclosed
US-20160244596-A1 FLAME RETARDANT FOR EPOXY RESIN CONTAINING PHOSPHONATE AND PHOSPHINATE FUNCTIONALITY ICL-IP AMERICA INC. 2016-08-25 US disclosed
US-7317119-B2 Process for the preparation of 9, 10-dihydro-9-OXA-10-organyloxyphosphaphenanthrene-10-oxide or -thione and derivatives of the same substituted on the phenyl groups Schill & Seilacher “Struktol” AG (DE) 2008-01-08 US disclosed
US-20050038278-A1 Process for the preparation of 9, 10-dihydro-9-OXA-10-organyloxyphosphaphenanthrene-10-oxide or -thione and derivatives of the same substituted on the phenyl groups SCHILL + SEILACHER "STRUKTOL" AKTIENGESELLSCHAFT (DE) 2005-02-17 US disclosed
US-5096935-A For addition polymers HOECHST AG (DE) 1992-03-17 US disclosed
US-5008426-A Photopolymerizable mixtures for moldings; printing plates, relief plates HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244596-A1 FLAME RETARDANT FOR EPOXY RESIN CONTAINING PHOSPHONATE AND PHOSPHINATE FUNCTIONALITY PFAS, PHOSPHO1, PPA1 KDM4E 345/4885MAP2K7 4157/4885GMNN 243/4885
US-20050038278-A1 Process for the preparation of 9, 10-dihydro-9-OXA-10-organyloxyphosphaphenanthrene-10-oxide or -thione and derivatives of the same substituted on the phenyl groups ADH1A, DHODH, PNPO KDM4E 3107/4885MAP2K7 1692/4885GMNN 1314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.