Sugi Predict

Sugi Predict / Compounds / SCHEMBL461599

SCHEMBL461599

SCHEMBL461599

CCCNC(=O)c1ccccc1C

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 7/20 0.64
▸ SMN1; SMN2 Q16637 3/20 0.64
▸ HTT P42858 2/20 0.62
▸ TSHR P16473 1/20 0.62
▸ NPC1 O15118 2/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ KMT2A Q03164 2/20 0.60
▸ MEN1 O00255 1/20 0.60
▸ MAPK1 P28482 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ P2RX7 Q99572 1/20 0.55
▸ KDM4E B2RXH2 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ NAAA Q02083 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31686014 1.00 HPGD (0.64) HPGDSMN1; SMN2HTTTSHRNPC1
Formic Acid SCHEMBL6321404 0.93 HPGD (0.57) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL486382 0.89 TSHR (0.80) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL10330496 0.88 TSHR (0.72) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL8205304 0.86 NAAA (0.72) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL11291380 0.86 NAAA (0.72) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL13310254 0.86 NAAA (0.72) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL13293962 0.86 NAAA (0.72) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL18646228 0.86 HPGD (0.55) HPGDSMN1; SMN2HTTTSHRNPC1
SCHEMBL2228385 0.86 MEN1 (0.54) HPGDSMN1; SMN2HTTTSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041930-B2 Slow-release silk thread and method for preparing the same SOUTH BAY INTERNATIONAL, INC. (US) 2024-07-23 — — US disclosed
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 — — WO disclosed
US-20230159446-A1 Methods and Compositions for Targeting Tregs using CCR8 Inhibitors NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) 2023-05-25 — — US disclosed
CN-109689671-A The modified polymer in surface 北卡罗来纳州大学 2019-04-26 — — CN disclosed
CN-109689670-A The modified polymer in surface 北卡罗来纳州大学 2019-04-26 — — CN disclosed
CN-108473478-A TBK/IKK inhibitor compounds and uses thereof 默克专利有限公司 2018-08-31 — — CN disclosed
EP-3081553-A1 SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF University of Tsukuba (JP) 2016-10-19 — — EP disclosed
EP-2825540-B1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2016-09-14 — — EP disclosed
WO-2016034507-A1 A PROCESS FOR THE PREPARATION OF 3-PHENYL/HETEROARYL-6-PHENOXY-8-ALKYLAMINO-IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-03-10 — — WO disclosed
EP-2614063-B1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2016-01-13 — — EP disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 — — US disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 — — US disclosed
WO-2012032031-A1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-03-15 — — WO disclosed
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF ASTELLAS PHARMA INC. (JP) 2010-09-30 — — US disclosed
US-20100113542-A1 TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR MERCK PATENT GESELLSCHAFT (DE) 2010-05-06 — — US disclosed
US-7576117-B1 Cyclic amine CCR3 antagonist TEIJIN LIMITED (JP) 2009-08-18 — — US disclosed
US-7417129-B2 Combinatorial libraries of monosaccharides ALCHEMIA PTY LTD (AU) 2008-08-26 — — US disclosed
US-20080182857-A1 Triazole Derivatives MERCK PATENT GMBH (DE) 2008-07-31 — — US disclosed
US-20070072136-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-5429941-A Use of analog ligand to reduce activation energy SCRIPPS RESEARCH INSTITUTE, THE 1995-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12041930-B2 Slow-release silk thread and method for preparing the same MLN, SENP7, SNAP29 HPGD 2593/4885SMN1; SMN2 865/4885HTT 3736/4885
US-20230159446-A1 Methods and Compositions for Targeting Tregs using CCR8 Inhibitors CCR8, CCR1, CCR3 HPGD 2003/4885SMN1; SMN2 4731/4885HTT 4727/4885
US-20080182857-A1 Triazole Derivatives HSP90AB1, HSP90AA1, HSP90B1 HPGD 1350/4885SMN1; SMN2 4072/4885HTT 1286/4885
US-20100113542-A1 TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR HSP90AB1, HSP90AB2P, HSP90AA1 HPGD 959/4885SMN1; SMN2 3118/4885HTT 337/4885
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF TRPV1, FGFR3, GPR17 HPGD 1224/4885SMN1; SMN2 3213/4885HTT 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.