SCHEMBL4863930

SCHEMBL4863930

CCCCCCCCCCCC(=O)Nc1ccc(C=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB11 A5LHX3 2/20 0.63
PSMA7 O14818 2/20 0.63
PSMB1 P20618 2/20 0.63
PSMA1 P25786 2/20 0.63
PSMA2 P25787 2/20 0.63
PSMA3 P25788 2/20 0.63
PSMA4 P25789 2/20 0.63
PSMB8 P28062 2/20 0.63
PSMB9 P28065 2/20 0.63
PSMA5 P28066 2/20 0.63
PSMB4 P28070 2/20 0.63
PSMB6 P28072 2/20 0.63
PSMB5 P28074 2/20 0.63
PSMB10 P40306 2/20 0.63
PSMB3 P49720 2/20 0.63
PSMB2 P49721 2/20 0.63
PSMA6 P60900 2/20 0.63
PSMA8 Q8TAA3 2/20 0.63
PSMB7 Q99436 2/20 0.63
SOAT2 O75908 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9122651 1.00 PSMB11 (0.63) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL21597970 1.00 PSMB11 (0.63) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL3865176 1.00 PSMB11 (0.63) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL10891781 1.00 PSMB11 (0.63) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL10879959 0.98 PSMB11 (0.61) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL14195863 0.96 TP53 (0.59) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL2739420 0.94 ALDH1A1 (0.59) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL9858666 0.88 ENPP2 (0.71) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL9510547 0.88 ENPP2 (0.71) PSMB11PSMA7PSMB1PSMA1PSMA2
SCHEMBL675018 0.88 ENPP2 (0.71) PSMB11PSMA7PSMB1PSMA1PSMA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE32311-E ANTIBIOTICS ELI LILLY AND COMPANY (US) 1986-12-16 US claimed
US-4396543-A Derivatives of A-21978C cyclic peptides ELI LILLY AND COMPANY (US) 1983-08-02 US claimed
US-7326407-B2 Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2008-02-05 US disclosed
US-20060099159-A1 Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2006-05-11 US disclosed
US-7008935-B2 Amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2006-03-07 US disclosed
US-20040198977-A1 Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof SOCIETE L'OREAL S.A. (FR) 2004-10-07 US disclosed
EP-1454896-A1 Amine, amide, sulfonamide and carbamate derivatives of benzylidenemalonoc acid salts photoprotective cosmetic compositions containing them L'OREAL (FR) 2004-09-08 EP disclosed
EP-0435334-B1 Silver halide color photographic material containing yellow colored cyan coupler FUJI PHOTO FILM CO LTD (JP) 1997-11-05 EP disclosed
US-5561040-A SILVER HALIDE COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1996-10-01 US disclosed
EP-0446863-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
US-5476759-A Containing a coupler which releases a development inhibitor FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US disclosed
US-4483918-A CONTAINING 5-PYRAZOLONE MAGNETA COUPLER AND AROMATIC TERTIARY AMINE-DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1984-11-20 US disclosed
US-4463085-A SILVER HALIDE EMULSION, MAGENTA COUPLER CONTAINING PYRAZOL-5-ONE RING, AND PIPERIDINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-07-31 US disclosed
US-4455363-A Heat-developable color photographic material with polymeric color coupler FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4436808-A MAGENTA COLOR IMAGE FORMING POLYMER COUPLE FROM A PYRAZOLINE-CONTAINING MONOMER FUJI PHOTO FILM CO., LTD. (JP) 1984-03-13 US disclosed
US-4413054-A WITH 4-ARYLTHIO-5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1983-11-01 US disclosed
EP-0081768-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1983-06-22 EP disclosed
US-4385111-A CONTAINING A 4-(2-ALKOXYARYLTHIO)-5-PYR-ZOLONE MAGENTA COUPLER AND SPIROBIINDENE MULTI-ETHER, ESTER, SULFONATE OR CARBAMATE AS STABILIZLERE FUJI PHOTO FILM CO., LTD. (JP) 1983-05-24 US disclosed
US-4383027-A 1-PHENYL-3-ANILINO-4-PHENYLTHIO-5-PYRAZOLONE, 1-PHENYL-3-PYRAZOLIDONE FUJI PHOTO FILM CO., LTD. (JP) 1983-05-10 US disclosed
US-4351897-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1982-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060099159-A1 Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof ACMSD, KDM6B, AADAC PSMB11 2226/4885PSMA7 2251/4885PSMB1 2724/4885
US-20040198977-A1 Novel amine, amide, sulphonamide and carbamate derivatives of benzalmalonic salts and photoprotective cosmetic compositions comprised thereof ACMSD, KDM6B, AADAC PSMB11 2226/4885PSMA7 2251/4885PSMB1 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.