Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25445337 | 0.88 | HPGD (0.59) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL6468546 | 0.77 | RAB9A (0.68) | MAPK1TSHRHPGDMEN1KMT2A | |
| SCHEMBL12375168 | 0.76 | MAPK1 (0.70) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL4547816 | 0.76 | CA1 (0.63) | TSHRHPGDGAAKMT2AALDH1A1 | |
| SCHEMBL12211276 | 0.76 | HPGD (0.58) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL12375175 | 0.76 | HPGD (0.65) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL18033560 | 0.75 | ALDH1A1 (0.56) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL7950040 | 0.74 | RAB9A (0.60) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL27554760 | 0.74 | HPGD (0.54) | MAPK1TSHRANPEPHPGDGAA | |
| SCHEMBL19296280 | 0.74 | TSHR (0.58) | MAPK1TSHRANPEPHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |