Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | SMO | Q99835 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25445337 | 0.85 | HPGD (0.59) | HPGDKMT2AGAALMNAL3MBTL1 | |
| SCHEMBL27554760 | 0.83 | HPGD (0.54) | EPHX2PPARGHPGDKMT2AGAA | |
| SCHEMBL13608946 | 0.82 | KMT2A (0.67) | CA1CA2CA7CA14EPHX2 | |
| SCHEMBL12375175 | 0.82 | HPGD (0.65) | SMOHPGDKMT2AGAALMNA | |
| SCHEMBL13609110 | 0.82 | PPARA (0.67) | CA1CA2CA7CA14EPHX2 | |
| SCHEMBL13609098 | 0.81 | KMT2A (0.62) | CA1CA2CA7CA14EPHX2 | |
| SCHEMBL13609113 | 0.81 | PKM (0.57) | CA1CA2CA7CA14EPHX2 | |
| SCHEMBL13575658 | 0.80 | PPARG (0.56) | EPHX2PPARGSMOHPGDKMT2A | |
| SCHEMBL24135058 | 0.80 | PPARG (0.65) | CA1CA2CA7CA14EPHX2 | |
| SCHEMBL7955857 | 0.80 | HPGD (0.54) | HPGDKMT2AGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884032-B2 | Trioxane monomers and dimers | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20120108545-A1 | Trioxane Monomers and Dimers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | JOHNS HOPKINS UNIVERSOTY (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108545-A1 | Trioxane Monomers and Dimers | CDK10, TMSB10, CASP10 | CA1 262/4885CA2 1233/4885CA7 2114/4885 |
| US-20090291923-A1 | TRIOXANE DIMERS HAVING HIGH ANTICANCER AND LONG-LASTING ANTIMALARIAL ACTIVITIES | HCCS, XPO5, DHX15 | CA1 2425/4885CA2 838/4885CA7 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.