Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625537 | 0.79 | MAPK14 (0.44) | AKT1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29432338 | 0.78 | MAPK14 (0.43) | AKT1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL26098879 | 0.73 | MAPKAPK2 (0.39) | JAK2MAPK14MAPK13MAPK12GSK3A | |
| SCHEMBL30916119 | 0.72 | NOTUM (0.47) | S1PR1S1PR3KDM1ABCHEACHE | |
| SCHEMBL20539302 | 0.72 | NOTUM (0.47) | S1PR1S1PR3KDM1ABCHEACHE | |
| SCHEMBL15311783 | 0.72 | NISCH (0.42) | S1PR1S1PR3BCHEACHEHTR1A | |
| SCHEMBL19072688 | 0.71 | MAPK14 (0.48) | AKT1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3446348 | 0.71 | TRPA1 (0.48) | AKT1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5871204 | 0.70 | PARP10 (0.46) | MAPK14GSK3AGSK3BCDK5S1PR1 | |
| SCHEMBL4864309 | 0.69 | AKT1 (0.39) | AKT1MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320835-B2 | Phosphorescent material | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20050196637-A1 | Phosphorescent material | LG CHEM, LTD. (KR) | 2005-09-08 | — | — | US | disclosed |