SCHEMBL28625537

SCHEMBL28625537

Fc1ccc(-c2cccnc2-c2ccc(F)cc2F)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 6/20 0.44
MAPK13 O15264 3/20 0.44
MAPK12 P53778 3/20 0.44
MAPK11 Q15759 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
AKT1 P31749 1/20 0.43
PTPRC P08575 2/20 0.40
CTSL P07711 1/20 0.40
CTSS P25774 1/20 0.40
PTPN13 Q12923 1/20 0.40
KMO O15229 1/20 0.40
TDP2 O95551 1/20 0.39
NSD2 O96028 1/20 0.39
ABL1 P00519 1/20 0.39
PLCG1 P19174 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432338 0.98 MAPK14 (0.43) MAPK14MAPK13MAPK12MAPK11MEN1
SCHEMBL19072688 0.87 MAPK14 (0.48) MAPK14MAPK13MAPK12MAPK11MEN1
SCHEMBL19248544 0.82 ALDH1A1 (0.46) MAPK14MAPK13MAPK12MAPK11MEN1
SCHEMBL27843562 0.82 MAPK13 (0.42) MAPK14MAPK13MAPK12MAPK11MEN1
SCHEMBL4864309 0.80 AKT1 (0.39) MAPK14MAPK13MAPK12MAPK11AKT1
SCHEMBL3446348 0.80 TRPA1 (0.48) MAPK14MAPK13MAPK12MAPK11MEN1
SCHEMBL27789183 0.80 MAPK14 (0.43) MAPK14MEN1KMT2AAKT1KMO
SCHEMBL15674427 0.80 MAPK14 (0.44) MAPK14MAPK13MAPK12MAPK11FEN1
SCHEMBL19072691 0.80 TRPV1 (0.46) MAPK14MAPK13MAPK12MAPK11AKT1
SCHEMBL4864249 0.79 AKT1 (0.41) MAPK14MAPK13MAPK12MAPK11AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113178464-B Organic light emitting display panel and display device 武汉华星光电半导体显示技术有限公司 2024-02-02 CN disclosed
CN-116761805-A Novel heterocyclic compound and organic light-emitting device comprising same 韩国深通新材料株式会社 2023-09-15 CN disclosed
CN-116670112-A Novel spirofluorene compound and organic light-emitting device comprising same 韩国深通新材料株式会社 2023-08-29 CN disclosed
CN-115697002-A Electroluminescent device and manufacturing method thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-02-03 CN disclosed
CN-115548240-A Gradient doped white organic electroluminescent device and preparation method thereof 中国科学院长春应用化学研究所 2022-12-30 CN disclosed
CN-113178464-A Organic light emitting display panel and display device 武汉华星光电半导体显示技术有限公司 2021-07-27 CN disclosed