Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625537 | 0.80 | MAPK14 (0.44) | AKT1FEN1TDO2MAPK14MAPK13 | |
| SCHEMBL28249915 | 0.80 | TDP2 (0.41) | KITPIM1 | |
| SCHEMBL29432338 | 0.79 | MAPK14 (0.43) | AKT1FEN1TDO2MAPK14MAPK13 | |
| SCHEMBL28891614 | 0.76 | DAPK3 (0.46) | FEN1TGFBR1MAP4K4PIM1PRKACA | |
| SCHEMBL19072688 | 0.75 | MAPK14 (0.48) | AKT1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3446348 | 0.72 | TRPA1 (0.48) | AKT1TDO2MAPK14MAPK13MAPK12 | |
| SCHEMBL30117487 | 0.72 | TGFBR1 (0.71) | TGFBR1CDC7ROCK2PIM1PRKACA | |
| SCHEMBL15638898 | 0.72 | TGFBR1 (0.71) | TGFBR1CDC7ROCK2PIM1PRKACA | |
| SCHEMBL19248544 | 0.71 | ALDH1A1 (0.46) | AKT1TDO2MAPK14MAPK13MAPK12 | |
| SCHEMBL27843562 | 0.71 | MAPK13 (0.42) | AKT1MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320835-B2 | Phosphorescent material | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20050196637-A1 | Phosphorescent material | LG CHEM, LTD. (KR) | 2005-09-08 | — | — | US | disclosed |