Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.46 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864306 | 0.76 | MAPKAPK2 (0.41) | MAPKAPK2PLK4DAPK3DYRK3PRKD3 | |
| SCHEMBL28105602 | 0.76 | KMO (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL3446349 | 0.75 | NR4A2 (0.54) | MAP4K4PIM1MAPK1DYRK1ACLK4 | |
| SCHEMBL3445363 | 0.75 | TDO2 (0.52) | MAPKAPK2PLK4DAPK3DYRK3PRKD3 | |
| SCHEMBL29804758 | 0.72 | NPC1 (0.67) | ITKKDRNPC1RAB9ACYP19A1 | |
| SCHEMBL27800723 | 0.72 | NPC1 (0.67) | ITKKDRNPC1RAB9ACYP19A1 | |
| SCHEMBL16242291 | 0.71 | KMO (0.47) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2061664 | 0.71 | RAB9A (0.71) | ITKKDRNPC1RAB9ACYP19A1 | |
| SCHEMBL29496847 | 0.71 | RAB9A (0.71) | ITKKDRNPC1RAB9ACYP19A1 | |
| SCHEMBL19072696 | 0.71 | KMO (0.54) | MAPK12MAPK13MAPK14NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816016-B1 | hexacoordinated Indium complex made of ligand 1,1-bis(trifluoromethyl)-2-(diphenylphosphino)-ethanol and bis-cyclometallated Ir 2-(2,4-difluoro-3-perfluoroisopropyl-phenyl)-4-carbazolyl-pyridine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-19 | — | — | US | disclosed |
| US-7320835-B2 | Phosphorescent material | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20050196637-A1 | Phosphorescent material | LG CHEM, LTD. (KR) | 2005-09-08 | — | — | US | disclosed |