Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328490 | 0.83 | KMT2A (0.42) | KMT2AMEN1TSHRHPGDMAPT | |
| SCHEMBL8777036 | 0.82 | KMT2A (0.50) | KMT2AMEN1TSHRHPGDMAPT | |
| SCHEMBL10041973 | 0.76 | POLB (0.51) | KMT2AMEN1HPGDMAPTPOLB | |
| SCHEMBL266382 | 0.76 | POLB (0.51) | KMT2AMEN1HPGDMAPTPOLB | |
| SCHEMBL10050934 | 0.76 | POLB (0.51) | KMT2AMEN1HPGDMAPTPOLB | |
| SCHEMBL5918159 | 0.74 | MEN1 (0.42) | KMT2AMEN1TSHRHPGDMAPT | |
| SCHEMBL11292055 | 0.73 | KMT2A (0.66) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL27285877 | 0.73 | MEN1 (0.43) | KMT2AMEN1TSHRHPGDMAPT | |
| SCHEMBL11082940 | 0.72 | MEN1 (0.41) | KMT2AMEN1HPGDMAPTPOLB | |
| SCHEMBL11082943 | 0.72 | MEN1 (0.41) | KMT2AMEN1HPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317177-A | The preparation method of pyrimidine salicylic acid oxime ester compound and application as herbicide | 常州大学 | 2019-10-11 | — | — | CN | disclosed |
| US-7329761-B2 | Substituted imides | CELGENE CORPORATION (US) | 2008-02-12 | — | — | US | disclosed |
| US-20050090516-A1 | Novel substituted imides | MULLER GEORGE W (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090516-A1 | Novel substituted imides | TNF, MIF, TNFRSF1A | KMT2A 1420/4885MEN1 3883/4885TSHR 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.