Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284437 | 0.78 | TSHR (0.42) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL4230692 | 0.76 | MAPK1 (0.40) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL4864675 | 0.73 | KMT2A (0.51) | MEN1KMT2AMAPTMAPK1L3MBTL1 | |
| SCHEMBL10839725 | 0.73 | MAPT (0.30) | TDP1MAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL8777036 | 0.72 | KMT2A (0.50) | MEN1KMT2AMAPTPTGS1PTGS2 | |
| SCHEMBL10050934 | 0.67 | POLB (0.51) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL10041973 | 0.67 | POLB (0.51) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL266382 | 0.67 | POLB (0.51) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL27425745 | 0.66 | MEN1 (0.47) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL5918159 | 0.65 | MEN1 (0.42) | MEN1KMT2AMAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1005376-B | Herbicides containing 5- (2-chloro-4-trifluoromethylphenoxy) -2-nitro-alpha-substituted acetophenone and/or oxime derivative as active ingredient and method for eliminating undesirable weeds | 旭化成工业株式会社 | 1989-10-11 | — | — | CN | disclosed |
| CN-85109609-A | Contain the acetophenone of 5-(2-chloro-4-4-trifluoromethylphenopendant)-2-nitro-alpha-substituted and/or derivative oxime as the weed killer herbicide of active ingredient and eliminate unwanted method for weed | — | 1986-11-05 | — | — | CN | disclosed |