Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041973 | 1.00 | POLB (0.51) | POLBMAPTNPSR1MAPK1TDP1 | |
| SCHEMBL10050934 | 1.00 | POLB (0.51) | POLBMAPTNPSR1MAPK1TDP1 | |
| SCHEMBL5918159 | 0.84 | MEN1 (0.42) | POLBMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11082943 | 0.82 | MEN1 (0.41) | POLBMAPTMEN1KMT2AGAA | |
| SCHEMBL11082940 | 0.82 | MEN1 (0.41) | POLBMAPTMEN1KMT2AGAA | |
| SCHEMBL27425745 | 0.80 | MEN1 (0.47) | MAPTMAPK1TDP1L3MBTL1MEN1 | |
| SCHEMBL11313374 | 0.79 | ALDH1A1 (0.46) | MAPTNPSR1MAPK1TDP1MEN1 | |
| SCHEMBL11313376 | 0.79 | ALDH1A1 (0.46) | MAPTNPSR1MAPK1TDP1MEN1 | |
| SCHEMBL31072922 | 0.79 | POLB (0.46) | POLBMAPTNPSR1MAPK1TDP1 | |
| SCHEMBL8777036 | 0.79 | KMT2A (0.50) | POLBMAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |
| EP-0557274-B1 | RECOVERY OF PALLADIUM | HENKEL CORP (US) | 1994-09-14 | — | — | EP | claimed |
| CN-104557670-B | Fullerene and 3,4 dihydro pyrrole derivates and preparation method thereof | 上海大学 | 2017-10-24 | — | — | CN | disclosed |
| EP-1655070-B1 | OXIDATION CATALYST | ASAHI KASEI CHEMICALS CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| CN-104557670-A | Fullereno-3,4-dihydropyrrole derivative and preparation method thereof | UNIV SHANGHAI | 2015-04-29 | — | — | CN | disclosed |
| US-8133834-B2 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8076343-B2 | Benzimidazoles useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-12-13 | — | — | US | disclosed |
| US-20100069670-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20070099920-A1 | Benzimidazoles useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2007-05-03 | — | — | US | disclosed |
| US-20060229471-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1655070-A1 | OXIDATION CATALYST | Asahi Kasei Chemicals Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| WO-1999018065-A1 | CHIRAL AMINES | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-04-15 | — | — | WO | disclosed |
| US-5654458-A | PALLADIUM CHLORIDE COMPLEX WITH ETHER OXIME | HENKEL CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| EP-0557274-B1 | RECOVERY OF PALLADIUM | HENKEL CORP (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0083293-B1 | REMOVAL OF ACRYLONITRILE FROM LATEX WITH OXIMES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4365027-A | TO FORM CYANOETHYL OXIMINO ETHER LINKAGE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| US-RE30634-E | INSECTICIDES | SHELL OIL COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4079149-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069670-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | POLB 549/4885MAPT 3864/4885NPSR1 4133/4885 |
| US-20070099920-A1 | Benzimidazoles useful as inhibitors of protein kinases | PDK1, AURKC, PIM3 | POLB 2207/4885MAPT 2133/4885NPSR1 4857/4885 |
| US-20060229471-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | POLB 549/4885MAPT 3864/4885NPSR1 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.