SCHEMBL4865170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4859116	0.87	CYP1A2 (0.72)	PDE5AMAPK1KDM4EPOLBRAD52
	SCHEMBL1085431	0.87	PDE5A (1.00)	PDE5AMAPK1KDM4ESLC6A3MEN1
	SCHEMBL5138849	0.86	PDE5A (0.82)	PDE5AMAPK1KDM4EPOLBRAD52
	SCHEMBL16404467	0.86	RAD52 (0.80)	PDE5AMAPK1KDM4EPOLBRAD52
	SCHEMBL12176090	0.85	LMNA (0.72)	PDE5AMAPK1POLBRAD52RXFP1
	SCHEMBL1083823	0.85	MEN1 (0.79)	PDE5AKDM4EPOLBRAD52ABCG2
	SCHEMBL2845653	0.84	APP (0.76)	PDE5APOLBKMT2AACP1
	SCHEMBL16404344	0.84	POLB (0.70)	PDE5AMAPK1POLBRAD52RXFP1
	SCHEMBL4867362	0.84	PDE5A (0.82)	PDE5AMAPK1KDM4ESLC6A3ABCG2
	SCHEMBL4868103	0.84	PDE5A (0.82)	PDE5AMAPK1KDM4EPOLBSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.