SCHEMBL4865588

SCHEMBL4865588

O=C(O)Oc1ccc(C(=O)c2cccc(OC(=O)O)c2OC(=O)O)cc1OC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.43
LMNA P02545 1/20 0.43
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.41
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RAB9A P51151 1/20 0.41
ELANE P08246 2/20 0.40
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
TOP1 P11387 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 1/20 0.37
HPSE Q9Y251 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4875288 0.84 MAPK1 (0.53) MAPK1LMNATSHRALDH1A1GAA
SCHEMBL376979 0.80 TSHR (0.55) LMNATSHRALDH1A1GAAKDM4E
SCHEMBL8456235 0.77 ATM (0.55) TSHRALDH1A1GAAKDM4ERAB9A
SCHEMBL9419481 0.75 STS (0.49) TSHRALDH1A1GAAKDM4ERAB9A
SCHEMBL1728306 0.74 MAPK1 (0.47) MAPK1TSHRALDH1A1GAAKDM4E
SCHEMBL7612493 0.74 ALDH1A1 (0.54) TSHRALDH1A1GAAKDM4ERAB9A
Water SCHEMBL2704404 0.72 MAPK1 (0.46) MAPK1TSHRALDH1A1GAAKDM4E
SCHEMBL3679424 0.72 ADORA3 (0.43) MAPK1TSHRALDH1A1GAAKDM4E
SCHEMBL11764286 0.71 CYP1A2 (0.64) TSHRALDH1A1GAAKDM4ERAB9A
SCHEMBL28412672 0.70 SLC6A3 (0.57) MAPK1LMNAALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7471360-B2 Liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2008-12-30 US disclosed
US-20070046870-A1 Liquid crystal display device KONICA MINOLTA OPTO, INC. 2007-03-01 US disclosed
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0648795-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0571899-B1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-B1 Method for forming patterned layers of heat-resistant polycondensates BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-A1 Method for forming patterned layers of heat-resistant polycondensates BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-15 EP disclosed
EP-0571899-A1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-01 EP disclosed