⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004309 | 0.79 | — | — | |
| SCHEMBL3622155 | 0.69 | — | — | |
| SCHEMBL5007258 | 0.65 | — | — | |
| SCHEMBL2302116 | 0.61 | NOS3 (0.33) | — | |
| SCHEMBL10656026 | 0.61 | — | — | |
| SCHEMBL2764539 | 0.60 | — | — | |
| SCHEMBL2074486 | 0.59 | HTR3A (0.35) | — | |
| SCHEMBL5009239 | 0.55 | — | — | |
| SCHEMBL1424748 | 0.54 | — | — | |
| SCHEMBL7382635 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191709-A | It can be used as the compound of indole amine 2,3-dioxygenase and/or tryptophan dioxygenase inhibitor | 德州大学系统董事会 | 2019-08-30 | — | — | CN | disclosed |
| US-20080300135-A1 | 5-Alkyl-7-Amino-6-Heteroaryl-1,2,4-Triazolo[1,5-A]Pyrimidine Compounds and Their Use for Controlling Harmful Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-04 | — | — | US | disclosed |
| US-7361743-B2 | Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides | PFIZER INC (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007006724-A1 | 5-ALKYL-7-AMINO-6-HETEROARYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AND USE THEREOF FOR THE PREVENTION OF FUNGAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | WO | disclosed |
| US-20060148722-A1 | Novel lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-07-06 | — | — | US | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |