Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486408 | 0.83 | MAPT (0.71) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL19322442 | 0.83 | MAPT (0.71) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL486125 | 0.82 | MAPT (0.73) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL29140301 | 0.80 | MAPT (0.67) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL30775588 | 0.80 | MAPT (0.67) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL486233 | 0.79 | ALDH1A1 (0.69) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL28264294 | 0.79 | MAPT (1.00) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL8166341 | 0.79 | ALDH1A1 (0.69) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL486340 | 0.79 | ALDH1A1 (0.69) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL9150171 | 0.78 | ALDH1A1 (0.68) | MAPTALDH1A1HTTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038874-A1 | METHOD FOR RELEASING AND LABELLING 0-GLYCANS | LEIDEN UNIVERSITY MEDICAL CENTER (NL) | 2011-04-07 | — | — | WO | claimed |
| EP-2305692-A1 | Method for releasing and labelling O-glycans | Academisch Ziekenhuis Leiden Acting Under The Name Leiden University Medical Center (NL) | 2011-04-06 | — | — | EP | claimed |
| EP-0480751-B1 | Method for labelling sugars | TAKARA SHUZO CO (JP) | 1995-08-02 | — | — | EP | claimed |
| US-5142031-A | Detection by bonding with 1-(p-methoxyphenyl)-3-methyl-5-pyraz olone; sensitivity, simplification | TAKARA SHUZO CO., LTD. (JP) | 1992-08-25 | — | — | US | claimed |
| EP-0480751-A1 | Method for labelling sugars | TAKARA SHUZO CO. LTD. (JP) | 1992-04-15 | — | — | EP | claimed |
| JP-4148865-A | — | — | None | — | — | JP | disclosed |
| US-9758486-B1 | Edaravone-gossypol derivatives with antitumor activities and a method of preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-09-12 | — | — | US | disclosed |
| EP-2145884-B1 | INDOLEDIONE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130078213-A1 | THROMBOPOIETIN MIMETICS | GLAXOSMITHKLINE LLC | 2013-03-28 | — | — | US | disclosed |
| US-8262881-B2 | Method for finger-printing heparins | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-09-11 | — | — | US | disclosed |
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | disclosed |
| WO-2011038874-A1 | METHOD FOR RELEASING AND LABELLING 0-GLYCANS | LEIDEN UNIVERSITY MEDICAL CENTER (NL) | 2011-04-07 | — | — | WO | disclosed |
| US-4452602-A | Process for dyeing leather with mixtures of dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 1984-06-05 | — | — | US | disclosed |
| EP-0072516-A1 | Chromium-complex dyestuffs | BAYER AG (DE) | 1983-02-23 | — | — | EP | disclosed |
| US-4221709-A | Azo pigments | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |
| US-4122278-A | INTERMEDIATES FOR DYES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-10-24 | — | — | US | disclosed |
| US-4101540-A | USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-07-18 | — | — | US | disclosed |
| US-4083839-A | Unsymmetrical mono sulfo containing 1:2 azo, azo chromium complex dyes | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-3970615-A | Unsymmetrical mono-sulfo containing chromium complexes of azo dyes | CIBA-GEIGY CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130078213-A1 | THROMBOPOIETIN MIMETICS | MPL, THPO, TEK | MAPT 4627/4885ALDH1A1 1012/4885HTT 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.