SCHEMBL486340

SCHEMBL486340

Cc1cc(=O)n(-c2ccc(Cl)cc2)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.69
MAPT P10636 9/20 0.69
KMT2A Q03164 9/20 0.69
KDM4E B2RXH2 6/20 0.69
MEN1 O00255 6/20 0.69
HTT P42858 5/20 0.69
GAA P10253 5/20 0.69
LMNA P02545 5/20 0.65
RECQL P46063 1/20 0.65
SMN1; SMN2 Q16637 6/20 0.63
TDP1 Q9NUW8 2/20 0.63
ALKBH5 Q6P6C2 2/20 0.58
NPC1 O15118 1/20 0.49
ALOX12 P18054 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HPGD P15428 1/20 0.47
POLB P06746 2/20 0.46
ALPL P05186 1/20 0.42
ALKBH3 Q96Q83 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486125 0.85 MAPT (0.73) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL486329 0.82 ALDH1A1 (0.65) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL4023307 0.82 MAPT (0.57) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL2484228 0.82 KMT2A (0.60) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL28264294 0.81 MAPT (1.00) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL8166341 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL486233 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL5203012 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL8592651 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL5425653 0.81 ALDH1A1 (0.68) ALDH1A1MAPTKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105940537-B Graphene composite, preparation method of graphene composite and electrode for lithium ion battery containing graphene composite 东丽先端材料研究开发(中国)有限公司 2020-12-08 CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
CN-105940537-A Graphene composite, preparation method of graphene composite and electrode for lithium ion battery containing graphene composite 东丽先端材料研究开发(中国)有限公司 2016-09-14 CN claimed
CN-104852051-A Graphene powder and preparation method and lithium ion battery containing graphene powder TORAY ADVANCED MATERIALS RES LAB CHINA CO LTD 2015-08-19 CN claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US disclosed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP disclosed
EP-3892734-B1 SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2024-08-28 EP disclosed
WO-2024150479-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
WO-2024150812-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
WO-2024150450-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
US-4052374-A UNSYMMETRICAL 1:2-CHROMIUM COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4045423-A MONOAZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-08-30 US disclosed
US-4045425-A Crystalline azopyrazolone acid dye E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-30 US disclosed
US-4024125-A Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 ALDH1A1 2333/4885MAPT 654/4885KMT2A 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.