SCHEMBL19961723

SCHEMBL19961723

c1ccc(-n2ccnc2-c2cccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.46
HTR2A P28223 1/20 0.46
KDM4E B2RXH2 2/20 0.43
MAPK9 P45984 1/20 0.42
MAPK10 P53779 1/20 0.42
GFER P55789 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
P2RX4 Q99571 2/20 0.41
GSK3B P49841 6/20 0.41
NISCH Q9Y2I1 1/20 0.41
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27729314 0.89 HTR2C (0.46) HTR2CHTR2AKDM4EMAPK9MAPK10
SCHEMBL4866386 0.84 NPC1 (0.46) HTR2CHTR2AKDM4EGFERNPSR1
SCHEMBL20980458 0.79 MAPK9 (0.37) HTR2CHTR2AKDM4EMAPK9MAPK10
SCHEMBL19353774 0.78 CYP3A4 (0.50) MAPK9MAPK10CYP1A2CYP3A4CYP2D6
SCHEMBL15316007 0.77 HTR2C (0.43) HTR2CHTR2AKDM4EMAPK9MAPK10
SCHEMBL20732576 0.77 ALOX5 (0.42) HTR2CHTR2AKDM4EMAPK9MAPK10
SCHEMBL5486071 0.77 HTR2C (0.66) HTR2CHTR2AKDM4ENISCHL3MBTL1
SCHEMBL24690220 0.77 MAPK9 (0.41) HTR2CHTR2AKDM4EMAPK9MAPK10
SCHEMBL16589069 0.76 L3MBTL1 (0.37) KDM4EMAPK9MAPK10P2RX4CYP1A2
SCHEMBL18729514 0.76 ALDH1A1 (0.35) HTR2CHTR2AKDM4EMAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 EP disclosed
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2018-03-15 US disclosed
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072753-A1 NOVEL ORGANIC HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE COMPRISING SAME OR10J3, CRY1, NR2E3 HTR2C 1536/4885HTR2A 1454/4885KDM4E 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.