Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197499 | 0.94 | CNR2 (0.50) | BCHEACHECNR2RAB9AGAA | |
| SCHEMBL2966006 | 0.87 | GAA (0.52) | GAALMNAKDM4EALDH1A1MAPT | |
| SCHEMBL3182762 | 0.85 | CNR2 (0.40) | CNR2GAALMNACNR1KDM4E | |
| SCHEMBL29364739 | 0.81 | ACHE (0.48) | BCHEACHECNR2RAB9AGAA | |
| Potassium Ion SCHEMBL338736 | 0.81 | ALDH1A1 (0.50) | BCHEACHECNR2GAALMNA | |
| SCHEMBL67964 | 0.81 | ALDH1A1 (0.50) | BCHEACHECNR2GAALMNA | |
| SCHEMBL5153019 | 0.81 | ALDH1A1 (0.50) | BCHEACHECNR2GAALMNA | |
| SCHEMBL1589913 | 0.81 | ALDH1A1 (0.50) | BCHEACHECNR2GAALMNA | |
| Zinc Ion SCHEMBL1589972 | 0.81 | ALDH1A1 (0.50) | BCHEACHECNR2GAALMNA | |
| SCHEMBL2955936 | 0.80 | GAA (0.46) | BCHEACHEGAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326517-B2 | Planographic printing plate material and preparing process of planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-02-05 | — | — | US | disclosed |
| US-20050260524-A1 | Planographic printing plate material and preparing process of planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2005-11-24 | — | — | US | disclosed |