Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.38 |
| ▸ | RARG | P13631 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.37 |
| ▸ | GLRB | P48167 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76574 | 0.85 | LMNA (0.41) | NR5A2NR5A1VCAM1CYP1A2CYP2C9 | |
| SCHEMBL29356716 | 0.85 | LMNA (0.41) | NR5A2NR5A1VCAM1CYP1A2CYP2C9 | |
| SCHEMBL28715272 | 0.85 | NR5A2 (0.36) | NR5A2NR5A1VCAM1RARGRXRA | |
| SCHEMBL29193192 | 0.85 | NR5A2 (0.43) | NR5A2NR5A1VCAM1RARGRXRA | |
| SCHEMBL28024266 | 0.82 | ALOX5 (0.46) | ALDH1A1POLBALOX5PTGS2 | |
| SCHEMBL5561251 | 0.80 | ESR1 (0.36) | NR5A2NR5A1VCAM1CYP1A2CYP2C9 | |
| SCHEMBL5181476 | 0.80 | NR1H4 (0.40) | RARGRXRAPPARGALDH1A1POLB | |
| SCHEMBL1530144 | 0.80 | NR5A2 (0.55) | NR5A2NR5A1RARGRXRAPPARG | |
| SCHEMBL30314144 | 0.80 | NR5A2 (0.55) | NR5A2NR5A1RARGRXRAPPARG | |
| SCHEMBL9423780 | 0.78 | NR5A2 (0.50) | NR5A2NR5A1RARGRXRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358365-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070185250-A1 | Stabilization of polyether polyols, polyester polyols and polyurethanes | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-08-09 | — | — | US | disclosed |
| US-20070037940-A1 | Romp with fluorinated groups | CIBA SPECIALTY CHEMICALS CORP. | 2007-02-15 | — | — | US | disclosed |
| US-7148382-B2 | Bathochromic mono- and bis-acylphosphine oxides and sulfides and their use as photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |
| US-20060246377-A1 | Halogenated oxime derivatives and the use thereof as latent acids | BASF SE (DE) | 2006-11-02 | — | — | US | disclosed |
| US-20060128903-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2006-06-15 | — | — | US | disclosed |
| US-20050131115-A1 | Stabilizer mixtures | GUGUMUS FRANCOIS (CH) | 2005-06-16 | — | — | US | disclosed |
| US-20040204613-A1 | Bathochromic mono-and bis-acylphosphine oxides and sulfides and their use as photoinitiators | IGM GROUP B.V. (NL) | 2004-10-14 | — | — | US | disclosed |
| US-20040082492-A1 | Biocidal plastics internal elements for mass transfer apparatus | CIBA SPECIALTY CHEMICALS CORP. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246377-A1 | Halogenated oxime derivatives and the use thereof as latent acids | AHR, ARSA, SULT1A1 | NR5A2 227/4885NR5A1 46/4885VCAM1 3469/4885 |
| US-20050131115-A1 | Stabilizer mixtures | C1R, C1S, C9 | NR5A2 2529/4885NR5A1 672/4885VCAM1 2530/4885 |
| US-20070185250-A1 | Stabilization of polyether polyols, polyester polyols and polyurethanes | PUF60, UFL1, XRCC5 | NR5A2 4506/4885NR5A1 3236/4885VCAM1 4760/4885 |
| US-20040204613-A1 | Bathochromic mono-and bis-acylphosphine oxides and sulfides and their use as photoinitiators | LBR, NR1H2, CBR1 | NR5A2 942/4885NR5A1 494/4885VCAM1 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.