Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369514 | 0.79 | LMNA (0.36) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL4554933 | 0.78 | LMNA (0.35) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL19058804 | 0.78 | POLB (0.37) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL4173041 | 0.75 | SMN1; SMN2 (0.36) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL4164008 | 0.75 | KMT2A (0.33) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL3753144 | 0.75 | KMT2A (0.33) | LMNAMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL4165780 | 0.74 | CYP1A2 (0.36) | LMNAL3MBTL1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13930385 | 0.74 | PKM (0.38) | MAPTL3MBTL1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4167426 | 0.73 | KMT2A (0.32) | LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL4161938 | 0.73 | L3MBTL1 (0.33) | LMNAL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965644-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |