Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492869 | 0.84 | DPP4 (0.38) | DPP4ALDH1A1CA14 | |
| SCHEMBL956549 | 0.79 | ALDH1A1 (0.42) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL18306605 | 0.79 | DPP4 (0.56) | DPP4ALDH1A1CA14 | |
| SCHEMBL4872179 | 0.79 | DPP4 (0.39) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL3178526 | 0.78 | ALDH1A1 (0.38) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL376711 | 0.73 | ALDH1A1 (0.37) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL3020149 | 0.73 | CA14 (0.49) | DPP4ALDH1A1CA14L3MBTL1 | |
| Alcohol SCHEMBL17363353 | 0.73 | SSTR4 (0.40) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL23540791 | 0.72 | ALDH1A1 (0.36) | DPP4ALDH1A1CA14L3MBTL1 | |
| SCHEMBL15668049 | 0.72 | SSTR4 (0.41) | DPP4ALDH1A1CA14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381738-B2 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-7288563-B2 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20050227960-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050192276-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2005-09-01 | — | — | US | disclosed |
| WO-2005079519-A2 | SUBSTITUTED BICYCLOALKYLAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005079496-A2 | SUBSTITUTED BICYCLOALKYLAMINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192276-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | CCR1, CCR2, BDKRB1 | DPP4 3375/4885ALDH1A1 2875/4885CA14 4117/4885 |
| US-20050227960-A1 | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity | CCR1, CCR2, CCR10 | DPP4 2937/4885ALDH1A1 1969/4885CA14 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.