Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866873 | 1.00 | TSHR (0.63) | TSHRALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL3742606 | 0.83 | TSHR (0.56) | TSHRALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL3742602 | 0.83 | TSHR (0.56) | TSHRALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL6020552 | 0.83 | TSHR (0.72) | TSHRALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL4858174 | 0.82 | MMP2 (0.56) | ALDH1A1MAPTTP53CTSLNPY5R | |
| SCHEMBL4857262 | 0.82 | NPY5R (0.62) | ALDH1A1HTTSMN1; SMN2MAPTCTSL | |
| SCHEMBL4858181 | 0.82 | MMP2 (0.56) | ALDH1A1MAPTTP53CTSLNPY5R | |
| SCHEMBL4857259 | 0.82 | NPY5R (0.62) | ALDH1A1HTTSMN1; SMN2MAPTCTSL | |
| SCHEMBL4866943 | 0.81 | GRIA1 (0.46) | KMT2ACYP2C9CYP2C19 | |
| SCHEMBL4866934 | 0.81 | GRIA1 (0.46) | KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |