Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858174 | 1.00 | MMP2 (0.56) | MMP2ADAMTS5NPY5RMMP9ALDH1A1 | |
| SCHEMBL4857259 | 0.90 | NPY5R (0.62) | MMP2NPY5RMMP9ALDH1A1ADAMTS4 | |
| SCHEMBL4857262 | 0.90 | NPY5R (0.62) | MMP2NPY5RMMP9ALDH1A1ADAMTS4 | |
| SCHEMBL4864009 | 0.88 | BMP1 (0.56) | MMP2NPY5RMMP9ALDH1A1BMP1 | |
| SCHEMBL4864003 | 0.88 | BMP1 (0.56) | MMP2NPY5RMMP9ALDH1A1BMP1 | |
| SCHEMBL4864934 | 0.85 | MMP2 (0.49) | MMP2ADAMTS5NPY5RMMP9ALDH1A1 | |
| SCHEMBL4864939 | 0.85 | MMP2 (0.49) | MMP2ADAMTS5NPY5RMMP9ALDH1A1 | |
| SCHEMBL4861466 | 0.84 | NPY5R (0.47) | MMP2NPY5RMMP9 | |
| SCHEMBL4861471 | 0.84 | NPY5R (0.47) | MMP2NPY5RMMP9 | |
| SCHEMBL3740541 | 0.83 | MMP2 (0.50) | MMP2ADAMTS5NPY5RMMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |