Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857262 | 1.00 | NPY5R (0.62) | NPY5RMMP9MMP2PSMB8PSMB5 | |
| SCHEMBL4858181 | 0.90 | MMP2 (0.56) | NPY5RMMP9MMP2ALDH1A1MAPT | |
| SCHEMBL4858174 | 0.90 | MMP2 (0.56) | NPY5RMMP9MMP2ALDH1A1MAPT | |
| SCHEMBL4864003 | 0.90 | BMP1 (0.56) | NPY5RMMP9MMP2ALDH1A1 | |
| SCHEMBL4864009 | 0.90 | BMP1 (0.56) | NPY5RMMP9MMP2ALDH1A1 | |
| SCHEMBL4861466 | 0.84 | NPY5R (0.47) | NPY5RMMP9MMP2 | |
| SCHEMBL4861471 | 0.84 | NPY5R (0.47) | NPY5RMMP9MMP2 | |
| SCHEMBL4864202 | 0.84 | KMT2A (0.49) | NPY5RALDH1A1MAPT | |
| SCHEMBL4864204 | 0.84 | KMT2A (0.49) | NPY5RALDH1A1MAPT | |
| SCHEMBL4866880 | 0.83 | KMT2A (0.45) | NPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | disclosed |