Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL486696

Cc1ccc(C(C)(C)C)cc1C(C)(C)C.N

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.37
TYR P14679 2/20 0.37
ESR1 P03372 1/20 0.37
NPC1 O15118 1/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1927914 0.98 TSHR (0.46) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL30786333 0.98 TSHR (0.46) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL22900080 0.82 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL8415470 0.82 PDE2A (0.47) TSHRMEN1MAPTKMT2AKIF11
SCHEMBL22380374 0.82 ESR1 (0.39) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL799856 0.82 KIF11 (0.44) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL26523765 0.82 TSHR (0.41) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL21288350 0.80 TSHR (0.48) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL29498849 0.79 TSHR (0.52) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL2009857 0.79 TSHR (0.52) TSHRALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8545988-B2 Polyetherimide and polyetherimide sulfone blends having automotive lighting applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-11401381-B2 Modified silicone compound, and thermosetting resin composition, prepreg, laminate plate and printed wiring board using same SHOWA DENKO MATERIALS CO., LTD. (JP) 2022-08-02 US disclosed
EP-3092271-B1 COMPATIBILIZED COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2022-03-16 EP disclosed
EP-2691476-B1 AIRCRAFT COMPONENT COMPRISING FLAME RETARDANT SILOXANE-CONTAINING POLYMER COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2021-04-21 EP disclosed
EP-2412743-B1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME HITACHI CHEMICAL CO LTD (JP) 2020-08-19 EP disclosed
EP-2935459-B1 POLYCARBONATE COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-12 EP disclosed
EP-3246363-B1 POLYIMIDE POLYPHENYLSULFONE BLENDS WITH IMPROVED FLAME RESISTANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-11-20 EP disclosed
EP-2991881-B1 INTERIOR TRAIN COMPONENTS HAVING LOW SMOKE AND LOW HEAT RELEASE, AND METHODS OF THEIR MANUFACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-30 EP disclosed
US-10196517-B2 Interior train components having low smoke and low heat release, and methods of their manufacture SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-05 US disclosed
EP-2630192-B1 POLYIMIDE POLYPHENYLSULFONE BLENDS WITH IMPROVED FLAME RESISTANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-01-09 EP disclosed
EP-0120130-A1 Polyetherimide bearing compositions GENERAL ELECTRIC COMPANY (US) 1984-10-03 EP disclosed
EP-0120183-A2 Continuous process for preparing polyetherimides GENERAL ELECTRIC COMPANY (US) 1984-10-03 EP disclosed
EP-0117395-A2 Liquid monomer feed pipe for continuous extrusion polymerization GENERAL ELECTRIC COMPANY (US) 1984-09-05 EP disclosed
US-4468506-A FROM ETHER-CONTAINING ARYLTETRACARBOXYLIC ACIDS GENERAL ELECTRIC COMPANY (US) 1984-08-28 US disclosed
US-4443591-A MELTING, CONVEYING, EXTRUSION GENERAL ELECTRIC COMPANY (US) 1984-04-17 US disclosed
US-4443592-A MELTS, KNEADING, SHEAR GENERAL ELECTRIC COMPANY (US) 1984-04-17 US disclosed
WO-1983004257-A1 PROCESS FOR MAKING POLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 1983-12-08 WO disclosed
EP-0095174-A2 Process for making polyetherimides GENERAL ELECTRIC COMPANY (US) 1983-11-30 EP disclosed
WO-1983003416-A1 POLYETHERIMIDE BLENDS GEN ELECTRIC (US) 1983-10-13 WO disclosed
EP-0091116-A1 Polyetherimide blends GENERAL ELECTRIC COMPANY (US) 1983-10-12 EP disclosed