Phosphoric Acid

Phosphoric Acid

SCHEMBL4867284

Nc1nc(N)nc(N)n1.O=P(O)(O)O.O=P(O)(O)OCC(CO)(CO)CO.O=P(O)(O)OCC(CO)(CO)CO

nearest known ligand 0.35

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 20/20 0.35
S1PR3 Q99500 19/20 0.35
S1PR4 O95977 3/20 0.33
S1PR5 Q9H228 3/20 0.33
S1PR2 O95136 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3991775 0.98 S1PR1 (0.36) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL30478040 0.95 S1PR1 (0.36) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL30433753 0.92 S1PR1 (0.33) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL9064986 0.85 BTN3A1 (0.35)
SCHEMBL16334425 0.85 BTN3A1 (0.35)
Phosphoric Acid SCHEMBL3381220 0.84 S1PR1 (0.36) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL23777275 0.82 FBP1 (0.37) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL133396 0.82 FBP1 (0.37) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL6702992 0.81 S1PR1 (0.38) S1PR1S1PR3S1PR4S1PR5S1PR2
SCHEMBL30340381 0.81 NUDT1 (0.45) S1PR1S1PR3S1PR4S1PR5S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255353-A1 METHOD FOR PREPARING MELAMINE SALT OF BIS(PENTAERYTHRITOL PHOSPHATE) PHOSPHORIC ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255353-A1 METHOD FOR PREPARING MELAMINE SALT OF BIS(PENTAERYTHRITOL PHOSPHATE) PHOSPHORIC ACID PHOSPHO1, PTEN, P2RY4 S1PR1 1718/4885S1PR3 2068/4885S1PR4 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.